Biochemistry. We find a single-nucleotide polymorphism (SNP) significantly associated with soapy-taste detection that is confirmed in the cilantro preference group.

Prog Mol Biol Transl Sci. 2012, 44 (8): 955-959.

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J Physiol (Lond).
We also estimate the heritability of cilantro soapy-taste detection in our cohort, showing that the heritability tagged by common SNPs is low, about 0.087.

Pliny claimed that coriander had important medicinal properties: It is not known why cilantro is so differentially perceived. Be on the lookout for your Britannica newsletter to get trusted stories delivered right to your inbox.





2010, 6: e1000993-10.1371/journal.pgen.1000993.Kurland MD, Newcomer MB, Peterlin Z, Ryan K, Firestein S, Batista VS: Discrimination of saturated aldehydes by the rat I7 olfactory receptor. Melissa Petruzzello is Assistant Editor of Plant and Environmental Science and covers a range of content from plants, algae, and fungi, to renewable energy and environmental engineering. 2010, 467: 1061-1073. 10.1126/science.1080190.Keller A, Zhuang H, Chi Q, Vosshall LB, Matsunami H: Genetic variation in a human odorant receptor alters odour perception. 10.1038/nature09534.Eriksson N, Benton GM, Do CB, Kiefer AK, Mountain JL, Hinds DA, Francke U, Tung JY: Genetic variants associated with breast size also influence breast cancer risk. For example, it is possible that the SNP rs72921001 could have a large effect on detection of a specific chemical in cilantro, but that the resulting effect on liking cilantro is much weaker, being modulated by environmental factors. Like our britannica stories? Am J Hum Genet.



10.1021/bi100976w.Araneda RC, Kini AD, Firestein S: The molecular receptive range of an odorant receptor. 10.1016/j.ajhg.2010.11.011.Tung JY, Do CB, Hinds DA, Kiefer AK, Macpherson JM, Chowdry AB, Francke U, Naughton BT, Mountain JL, Wojcicki A, Eriksson N: Efficient replication of over 180 genetic associations with self-reported medical data.

The key aroma components in cilantro consist of various aldehydes, in particular (E)-2-alkenals and Several families of genes are important for taste and smell. This has implications for the interpretation of our results. 10.1038/486S4a.Smith B: Perspective: complexities of flavour. In both the GWAS set and the replication set, all participants were of European ancestry. It is actually a dominant trait. She has her M.S.... In this study, participants were asked two questions about cilantro via research snippets:‘Does fresh cilantro taste like soap to you?’ (Yes/No/I’m not sure)‘Do you like the taste of fresh (not dried) cilantro?’ (Yes/No/I’m not sure)Among all 23andMe customers, 18,495 answered the first question (as either yes or no), 29,704 the second, and 15,751 both.

2012, 1: 8-10.1186/2044-7248-1-8.Knaapila A, Hwang LD, Lysenko A, Duke FF, Fesi B, Khoshnevisan A, James RS, Wysocki CJ, Rhyu M, Tordoff MG, Bachmanov AA, Mura E, Nagai H, Reed DR: Genetic analysis of chemosensory traits in human twins. It turns out that about 10-15% of the population has a set of genes that make cilantro taste like soap! Nat Genet. It would thus be interesting to study the genetics of cilantro taste/odor perception in a group without prior exposure to cilantro to reduce the environmental effect, using more direct measures of cilantro perception (i.e., having the subjects actually taste and smell cilantro).Through a GWAS, we have shown that a SNP, rs72921001, near a cluster of olfactory receptors is significantly associated with detecting a soapy taste to cilantro.

Participants also reported their age. 1855, London: H.G.

Nature. 10.1086/521987.Howie B, Fuchsberger C, Stephens M, Marchini J, Abecasis GR: Fast and accurate genotype imputation in genome-wide association studies through pre-phasing.
And, it sits right next to a cluster of odor-detecting genes, including one that is known to specifically recognize the soapy aromas in cilantro's bouquet.

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