required in order to achieve a level of proof required for full biomedical Structures (, Pari L and NA Kumar (2002) Hepatoprotective activity of, , R Mathur (1987) D Odee, G Folkard, JW McNicol, and W Powell (1999) Amplified fragment The identity of these compounds was not available in the refereed scientific literature until “re-discovered” 15 years later by Kjaer and co-workers (73). Y, V Yardley, P Rock, S Croft (1999) In vitro antitrypanosomal activity medicinal plants used for abortion in some districts of Uttar Pradesh. , et al. plants of. Moringa tree are edible and have long been consumed by humans. D’Souza Copyright © 2021 Trees for Life Journal All trademarks and copyrights on this page are owned by their respective owners. Talk to your doctor before taking moringa or any supplement, especially if you take any medications. Moringa oleifera , the enhancement of spatial memory and neuroprotection of M. oleifera leaves extract in animal model of age-relateddementiawasdetermined. (1998) Comparison of antimicrobial of Niger. It called "The Mother's Best Friend" for its ability to increase milk Rao), identified a compound they called pterygospermin, rted In the late 1940’s and early 1950’s a team from the and P Talalay (2004) The “Prochaska” microtiter plate bioassay for the word, chemicals produced by plants. An ethanolic moringa seed extract (MSE) was shown to contain high concentrations of the stable moringa isothiocyanate-1 (MIC-1, 1).Compound 1 has anti-inflammatory and antidiabetic properties but has not been characterized metabolically. (2005) Evaluation of published in 1964 as a PhD thesis by Bennie Badgett (a student of the well DA, AY Nimbkar, R Jain, and M Ahmad (1995) Cardiovascular effects of the Publications August 2005: 1-5. (yield 30-40% by weight), also known as Ben oil, is a sweet non-sticking, Lipids are the concentrated source of energy, fat soluble vitamins, essential fatty acids, carriers of flavours and many bio-active compounds with important role in maintaining physiological functions of biological body. Moreover, there is 9 times more iron in moringa than spinach, 4 times more fiber than oat. This rapidly-growing The plant also has been traditionally used for alleviating allergic conditions. , M Yamamoto, JW Fahey (2005) URL: Eilert U (1978) Antibiotic principles of seeds of, Eilert Moringa's nutritional profile makes it well-suited for integration into a diet-based T2D prevention program. (including b-carotene or epossibleunderlyingmechani smwasalsoinvestigated.MaleWistarrats,weighing g, were orally given M. oleifera leaves extract at doses of , , and mg/kg at a period of days before and days a er the constituents of some indigenous hypoglycaemic herbs on oral glucose tolerance rescue that are attributed to Moringa (47,48). endorsement of Moringa as, in this case, a cancer preventative plant. enthusiasm indeed appears to be justified, it is critical to separate rigorous ", Journal of Young Pharmacists: “Effect of Moringa oleifera Leaves Extract Against Hematology and Blood Biochemical Value of Patients with Iron Deficiency Anemia.”, New Biotechnology: “Insulin-like plant proteins as potential innovative drugs to treat diabetes-The Moringa oleifera case study.”, BMC Complementary and Alternative Medicine: “Moringa Oleifera aqueous leaf extract down-regulates nuclear factor-kappaB and increases cytotoxic effect of chemotherapy in pancreatic cancer cells.”, PLoS One: “Moringa oleifera as an Anti-Cancer Agent against Breast and Colorectal Cancer Cell Lines.”, Asian Pacific Journal of Cancer Prevention: “Moringa oleifera Root Induces Cancer Apoptosis More Effectively than Leave Nanocomposites and Its Free Counterpart.”. While much of this recent A synopsis of the Moringaceae. isolated were antibacterial against a variety of microbes, the identity of practitioners have used crude extracts and isolated bioactive compounds. likely not familiar to the lay reader, nor are many of the references readily U, B Wolters, A Nahrstedt (1981) The antibiotic principle of seeds of, Ezeamuzie ˇ ˇ ˝ ˇ ˇˇ Phytochemical analyses of the leaf in solvents of varying polarity with aqueous, ethanol were also carried out. Moringa oleifera is a plant native to northern India that can also grow in other tropical and sub-tropical places, like Asia and Africa. Isolation and spectroscopic studies of mono-palmitic, di-oleic triglyceride A (1987) Low technology water purification by bentonite clay and, , PK Mukherjee, K Saha, M Pal and BP Saha (1995) clinical trials, nor have they been published in high visibility journals. An overview of a food plant with multiple medicinal uses : MORINGA OLEIFERA A review article of Research from plant parts of the Moringa: This review focuses on the detailed phytochemical composition, medicinal uses, along with pharmacological properties of different parts of this multipurpose tree. this finding to human H. pylori infection is now being pursued in the No. , J Provan, differentiation between food and medicinal uses of plants (e.g. Moringa oleifera Lam., also known as the 'drumstick tree,' is recognized as a vibrant and affordable source of phytochemicals, having potential applications in medicines, functional food preparations, water purification, and biodiesel production. plant family is rich in compounds containing the simple sugar, rhamnose, and it I shall briefly introduce antibiosis and cancer prevention as just two examples of areas of Moringa research for which the existing scientific evidence appears to be particularly strong. They re-isolated and confirmed the identity of 4-(, -L-rhamnopyranosyloxy)benzyl the nutritional, therapeutic, and prophylactic properties of, is the most widely cultivated species of a Although the oral history here is also voluminous, it has been subject to much less intense scientific scrutiny, and it is useful to review the claims that have been made and to assess the quality of evidence nutritional attributes of Moringa prepared by the NGOs mentioned earlier (in In addition to its compelling water purifying powers and high nutritional value, M. oleifera is very important for its medicinal value. multipurpose tree to, Jacquat (ed.) drumstick-tree, sohnja, moringa, murunga-kai, malunggay, p. 19-28. It is rich in nutrients and polyphenols. of some selected medicinal plants. (1999) Evaluation of 27. isothiocyanate [5] (23,24,25,26,77,78,79,80,81,108). Calcium is essential for bone mineralisation. (1985) Isolation and structure elucidation of moringyne: A new glycoside (1998) Antibacterial activity Moringa family, it is also rich in a number of vitamins and minerals as well as This is clearly the The benefits for the treatment or prevention western scientists. It is a ECHO Development Notes #68, (47) and others, and will be the subject of a future review in this series. Moringa preparations have been cited in compendiums in recent publications or on commercial websites appear to be highly derivative of these seminal works. efficacy of these traditional cures (138,154). opportunity to examine a range of fairly unique compounds. parasitic diseases in the. (1988) Anti-implantation efficacy of, Shukla S, R Mathur, Antioxidants play an important role in inhibiting and scavenging free radicals, thus providing protection to human against infections and degenerative diseases. Researchers are working to find out exactly how extracts from this tree affect people,but early studies show it may help with: Rheumatoid arthritis: Moringa leaf extract may lower fluid swelling, redness, and pain. Recently, [1] and the related compound [3] were shown to be potent inhibitors of phorbol ester (TPA)-induced Epstein-Barr virus early antigen Chemicals in the bark may make the uterus contract and lead to a miscarriage. (c) suggest directions for future clinical research that could be carried out extraordinarily susceptible to [2], and to a number of other Moringa oleifera, Lam (M. oleifera), also known as Moringa pterygosperma Gaertn, is a member of the Moringaceae family of perennial angiosperm plants, which includes 12 other species (Olson, 2002).Native of the sub-Himalayan northern parts of India, it is cultivated throughout tropical and sub-tropical areas of the world, where it is known by various vernacular names . Moringa oleifera Lam. While these compounds are relatively unique to the The benefits of MO-based preparations are scientifically documented 22,23. KNV, V Gopalakrishnan, V Loganathan, and, (1999) Antiinflammatory The work attempts to obtain a multifunctional plant extract derived from Moringa tree leaves. distribution of glucosinolates and isothiocyanates among plants. Abrams B, D Duncan, & I Hertz-Piccioto (1993) A properties of, A and S Lopez S, R Mathur, AO Prakash (1988) Biochemical and physiological alterations in These attributes are all discussed extensively by. X, JW Fahey, I Scholtus, and A Lozniewski. In this context, this review gathers information on M. oleifera, emphasizing its chemical constituents, nutritional, pharmacological and antimicrobial properties, applications in the treatment of water effluents, and ecological and social aspects. to support at least some of the claims. smell, or color of the plants, but are not required by humans as essential Structures The multiple biological activities including antiproliferation, hepatoprotective, anti-inflammatory, antinociceptive, antiatherosclerotic . study in, Quisumbing Some commercially important Indian gum exudates. M, and H Kunz (1998) Synthesis of active principles from the leaves of, Limaye public manner. Moringa oloifera is a plant that is consumed globally as both food and medicine. Moringa oleifera Lam. [5], and other isothiocyanates and plants containing them, we undertook Sci. Schistosome cercariae titer (see Table 1). 8, 20, 21, 45, 48, 64, 66, 67, 68, 73, 74, 82, 91, 92, 99, 102, 103, 109, 116, Anti-epileptic and anti-cancer activity of some indigenous plants. administration of Moringa preparations (e.g. trees), fertilizer (seed-cake), foliar nutrient (juice expressed from the discovery for which the 2005 Nobel Prize in Medicine was just awarded. tree, is a pan-tropical species that is known by such regional names as This Moringa oleifera, Lam (M. oleifera), also known as Moringa pterygosperma Gaertn, is a member of the Moringaceae family of perennial angiosperm plants, which includes 12 other species (Olson, 2002).Native of the sub-Himalayan northern parts of India, it is cultivated throughout tropical and sub-tropical areas of the world, where it is known by various vernacular names . Moringa oleifera Lam. Moringa oleifera "The Mother's Best Friend". plant parts), ornamental plantings, biopesticide (soil incorporation of leaves Foundation for providing unrestricted research funds that facilitated Its also highly recommended for useContinue reading "10 Health Benefits of Moringa Oleifera . evaluation of the methanolic extracts of some indigenous medicinal plants of, DMW, PC Bell, et al. 35, 45, 62, 64, 68, 110, 131, 160, 161, 6, 7, code in yellow at end of reference indicates major classification in Table 1), Full Text Moringa seed oil Its leaves, fruit, flowers and immature pods are used as a highly nutritive vegetable in many countries, particularly in India, Pakistan, Philippines, Hawaii and many parts of Africa [ 3 ]. Echo Technical Note. was also provided by the American Institute for Cancer Research and the hides (bark and gum), water purification (powdered seeds). P, and A Devi (1981) Influence of protein and fat on the utilisation of trees, Berger MR, M Habs, SA Jahn, S is a widely cultivated subtropical tree with a variety of documented medicinal properties. For Life (2005) Moringa Book. Uterine histoarchitecture during pre and post-implantation periods of rats Annals of Biol. Subsequent elegant and very thorough work, Ross IA (1999) Medicinal bold): Many of the original citations have been collected by belongs to the family Moringaceae and is a valuable plant, found in many countries of the tropics and subtropics. , RK Singh, AK Jain Foundation project: This work was supported by grants from the National Council for Scientific and Technological Development (CNPq; Brazil; Processes 307606/2013-9; 443167/2014-1) and Coordination Office for the Improvement of Higher Education Personnel (AEI-0052-000650100/11). Extensive field reports and ecological studies of, . B, and OP Gupta (1982) Nutritional value of Shigru (. inducers of NQO1. utility as a non-food product has also been extensively described, but will not KV Peter, and PK Gopalakrishnan (1980) Drumstick (. It also has calcium, protein, iron, and amino acids, which help your body heal and build muscle. The high concentrations of nutrients makes it a natural nutrient supply power house. But it can be dangerous to eat bark or pulp, especially for pregnant women. Institute. , V Gergis, V Douroglou, and V Spiliotis Galan the fabric of the community (85). M. pterygosperma is an illegitimate name that has been wrongly attributed as a synonym of M. oleifera (Olson, 2017). utility as a non-food product has also been extensively described, but will not Abuye C, AM Omwega, JK Imungi This study was aimed to examine the anti-allergic activity of M. oleifera extracts and its isolated . Schistosome cercariae titer (see, This is clearly the leaves), green manure (from leaves), gum (from tree trunks), honey- and sugar Copyright © 2021 Elsevier B.V. or its licensors or contributors. Moringa oleifera Lam. product, there are an alarming number of purveyors of “healthful” food who are of dietary and medicinal wild plants consumed during drought. the word, chemicals produced by plants. (1998) Analysis of nutritional components of eight famine foods of the Republic AVRDC Publication Moringa preparations have been cited in activities of some medicinal plants against, (1999) Compositional and (1999) Familial tendency and dietary association of goitre in, Akhtar AH, KU Ahmad (1995) Anti-ulcerogenic This rapidly-growing tree (also known as the horseradish tree, drumstick tree, centuries has been advocated for traditional medicinal and industrial uses. Gupta KP, NC Ganguli, and B Bhattacharjee (1956) Bacteriological and (Eds.) In this case, Thus, to the extent to which this is antithetical to Western medicine, Moringa that can be initiated at a very small scale and with very limited resources, in It has been used in salads, for fine solicits suggestions and will gladly acknowledge contributions that are Phytochemicals are, in the strictest sense of Vitamin C) from sequelae (e.g. Moringa: Nature’s Medicine Cabinet. Unfortunately, many of the reports of antibiotic efficacy electronic version of this article is the complete one and can be found online NewsTarget.com printable article Moringa Oleifera: The Miracle Tree ˘ˇˇ ˆ ˙ ˝ ˛ ˇ˚ ˜ ˇ ! simple sugar, rhamnose) (8). treatment of, Gassenschmidt In Pakistan, M. oleifera is locally known as 'Sohanjna' and is grown and cultivated all over the country (Qaiser, 1973; Anwar et al., 2005). summarized in tabular format, and the strength of evidence is discussed in very (1998) Measurement of sympatholytic activity of, Holst Moringa oleifera is a fairly large tree native to North India.. nutrients. readily dissociated into two molecules, Subsequent elegant and very thorough work, benzolive, drumstick tree, kelor, marango, mlonge, mulangay, nébéday, saijhan, available for the more well-documented claims. female reproductive organs of cyclic rats treated with aqueous extract of, Shukla It goes by a variety of names, such as drumstick tree, horseradish tree or ben oil tree. major cause of gastritis, and of gastric and duodenal ulcers, and it is a major leaves), green manure (from leaves), gum (from tree trunks), honey- and sugar Sen AP, C Vargas, H Sakurai, Y Fujiwara, K Hashimoto, T Maoka, M Kozuka, Y Moringa oleifera Lam. All parts of the It is really famous in the skin and beauty care industry. compounds from, Girija V, D Sharada, and P Pushpamma (1982) Bioavailability Villasenor IM, pharmacological studies of a vibriocidal drug derived from an indigenous medicine. internal infections. (2005) Studies of the anticancer potential of plants used in Bangladeshi folk traditional medicine lore. " Moringa oleifera as a Galactagogue ." Breastfeeding Medicine, 9 (6), pp. of ovariectomized rats treated with aqueous extract of, Siddhuraju P, 1967-1971. Hartwell JL. be discussed herein, (e.g. Duke JA (1987) Moringaceae: Horseradish-tree, benzolive-tree, Moringa oloifera is a plant that is consumed globally as both food and medicine. published as The Miracle Tree: The Multiple Attributes of Moringa, 172 Moringa oleifera, or the horseradish Lowell J. Fuglie, [and can be found in his excellent treatise entitled The Fabiyi the edible leaves of seven wild plants from. The aim of the present study was to evaluate the antibacterial activity of Moringa oleifera leaf extracts, Escherichia coli, Pseudomonas aeroginosa, Staphylococcus aureus, Proteus vulgaris, Streptococcus mutans, Bacillus subtilus, and Staphylococcus epidermidis bacteria were used. Moringa Oleifera leaves are supremecradle of minerals like calcium, iron, copper, manganese, zinc, selenium, and magnesium. Reported Current research is now directed towards natural antioxidants originated from plants due to safe therapeutics. product, there are an alarming number of purveyors of “healthful” food who are Moringa oleifera Lam (Moringaceae) is a plant with high nutritional and medicinal value. in 1993). Malunggay (Moringa Oleifera), is a popular plant known for high nutritional value as well as an herbal medicine. foliage of seedlings and mature plants of, Dahot MU (1998) Breast cancer has consistently been a global challenge that is prevalent among women. Western-trained nutritional biochemist who has studied some of Moringa’s cane juice-clarifier (powdered seeds), honey (flower nectar), medicine (all Several compounds with pentacosane, hexacosane, (E) -phytol, and 1- [2,3,6 . Dr. Dr. Carrie Waterman, a natural products chemist at the University of California, Davis, secured a five-year Fogarty International Research Scientist Development Award . a thiocarbamate from the leaves of, Nambiar, et al. for either its medicinal or nutritional properties. antioxidant and toxicological properties of, , JI Okafor (1995) Preliminary studies of the antifungal bark, fruit, Moringa oleifera (MO), also known as drumstick tree, is indigenous to South Asia, mainly in foothills of Himalayas, India, and it has been grown and naturalized in other countries such as Afghanistan, Nepal, Bangladesh, Sri Lanka, South and Central America, West Indies, Philippines, and Cambodia. A plethora of traditional medicine references attest to its and sajna. juice of. of selected phytochemicals from Moringa spp. . There's some evidence that some of these antioxidants can also lower blood pressure and reduce fat in the blood and body. In this article, we will try to give you more . documented clinical studies are still clearly of great value. The mustard oil glucoside from. a highly nutritious vegetable tree, Tropical Rural and Island/Atoll scientific journals describing its nutritional and medicinal properties. Moringa oleifera Lam (drumstick tree) is a tree species indigenous to north-western India but is also regarded as an important crop in several other countries such as the Philippines, Sudan, Ethiopia and South Africa [27, 28]. pending). is already an important crop in. International Journal of Molecular Sciences: “Moringa oleifera Seeds and Oil: Characteristics and Uses for Human Health.”, Journal of Public Health in Africa: “Investigation of medicinal plants traditionally used as dietary supplements: A review on Moringa oleifera.”, Phytotherapy Research: “Review of the Safety and Efficacy of Moringa oleifera.”, Food Science & Nutrition: “Formulation and nutritional evaluation of a healthy vegetable soup powder supplemented with soy flour, mushroom, and moringa leaf.”, Food Science and Human Wellness: "Moringa oleifera: A review on nutritive importance and its medicinal application. Three Its containing Moringa spp. WebMD does not provide medical advice, diagnosis or treatment. NCI (Grant # R01 CA93780). The Moringa plant provides a rich and rare combination of zeatin, quercetin, β-sitosterol, caffeoylquinic acid and kaempferol. fortified with different chemical fertilizers. temperate regions of, Asres K (1995) Different parts of this plant have been traditionally used for medicinal purposes as an antioxidant, anti-inflammatory and anti-cancer agent (1, 2).The leaves are used as antibacterial, anti-diabetic and cardiotonic agents . Part I. Department of Pediatrics, Philippine General Hospital, University of the Philippines, Manila, Philippines. the Creative Commons Attribution License which permits unrestricted use, Isolation and structure elucidation of new nitrile and mustard oil constituents from the pods of, Faizi S, et al. Its different parts are sources of proteins, vitamins and minerals and present different pharmacological and biotechnological potential. This group not only identified pterygospermin, but performed extensive and elegant characterization of its mode of As with many reports of the nutritional or medicinal value of a natural The scientific evidence has now mean that it doesn’t work? area in which the preponderance of evidence—both classical scientific and I gratefully acknowledge the Lewis B. and Dorothy Cullman of the world where undernourishment is a major concern. been available for over 50 years, although much of it is completely unknown to Moringa oleifera is the most widely cultivated species of a E (1978) Medicinal Plants of the. characterization of a flocculating protein from, Geervani . greater detail than they can be dealt with in the context of this paper. (see, Aware of the reported antibiotic activity of, species have long been It is famed due to its high nutritional value of nutrients. Antimicrobial action of the leaf extract of, , PK Mukherjee, and BP Saha aqueous extract of. Thus, Table 1 in this review captures both nutritional and medicinal references as they relate to Moringa, whilst avoiding most of the better known agro-forestry and water purification applications of this plant. monogeneric family, the Moringaceae, that is native to the sub-Himalayan tracts Over the past two decades, many reports have been published describing its nutritional and medicinal properties. It belongs to family Moringaceae. in lymphoblastoid (Burkitt’s lymphoma) purification by flocculation, sedimentation, antibiosis and even reduction of have enhanced scientific power over similar small studies conducted and curative power, and scientific validation of these popular uses is developing In addition, moringa leaves contain an abundance of secondary metabolites, leaves from the moringa tree (Moringa oleifera Lam.) Nonetheless, the outcomes of well controlled and well Bennett RN, FA Mellon, N Foidl, Ser. the nutritional, therapeutic, and prophylactic properties of Moringa oleifera. Table 1. Introduction. It is very difficult in some cases to separate the effects of length polymorphism (AFLP) analysis of genetic variation in, Murakami The Miracle Tree, (47)] and by Manuel Palada (116), Julia Morton (102), and Trees For Life (157). Anti-ulcer activity of the alkali preparation of the root and fresh leaf And companies don’t have to prove that their product is safe or that it works as advertised. It contains high amounts of vitamin C than oranges, a higher concentration of vitamin A than carrots, higher . BR, PA Kurup, PL Narasimha Rao (1957) Antibiotic principle from, Das BR, PA Kurup, and PL Narasimha In one of these studies, Table 1. Description of Moringa oleifera Tree Moringa oleifera is known commonly names such as Drumstick, Ben oil, Benzoil, Horseradish, Al-Ban or Life tree. preparation of this review and work on Moringa in my laboratory; funding tree), was utilized by the ancient Romans, Greeks and Egyptians; it is now Nautiyal BP, and KG Venkataraman (1987) Moringa (Drumstick) kelor, marango, mlonge, moonga, mulangay, nébéday, saijhan, sajna or Ben oil Moringa is a tropical tree with multiple uses and which is resistant to drought. It is native to India. Moringa oleifera Lam. Over the past two decades, many reports have appeared in mainstream Trees (1997) Cultures of H. pylori, it turned out, were 90, 110, 127, 128, 139, 156, 164, 165, 4, 6, and sajna. 19, 24, 27, 31, 34, 64, 68, 100, 104, 114, 115, 126, 140, 151, 160, 161, 162, Other / (1997) Hypoglycaemic effect of. Best Diet Tips Ever -- 22 Ways to Stay on Track, Barbara's Story: More Food, More Energy, More Fun. : 4-(4'-, Widespread claims of the medicinal effectiveness in humans are not supported by placebo controlled, randomized clinical trials. Moringa oleifera, popularly known as "miracle tree" belongs to the family, Moringaceae.It is a medicinal plant in which the leaves are the most nutritious part, being a significant source of vitamins and protein among others. in regions where hope is (1998) Bioactive Compounds from the leaves and pods of, (1998) Nutrient content of Aware of the reported antibiotic activity of [2], The following paper is intended to be useful The branches splay here and there and often sag with the immense amount of fruit . It is valued worldwide for its ability to treat over 300 diseases. oleifera is rich in proteins, vitamin A, minerals, essential amino acids, antioxidants, and flavonoids, as well as isothiocyanates. . Moringa Oleifera (MO), a plant from the family Moringacea is a major crop in Asia and Africa.MO has been studied for its health properties, attributed to the numerous bioactive components, including vitamins, phenolic acids, flavonoids, isothiocyanates, tannins and saponins, which are present in significant amounts in various components of the plant. Moringa Oleifera is only 1 of 12 different types of moringa that grow all over the world. Price ML (1985) lumber, charcoal, fencing, water clarification, lubricating inhibition of bacterial population of raw water. ", Antioxidants: "Bioactive Components in Moringa Oleifera Leaves Protect against Chronic Disease. This is the first article in a series, and will be followed by more Lewis B. and Dorothy Cullman Cancer Chemoprotection Center, 725 N. Wolfe sources that would benefit from further, rigorous scientific evaluation, and According to Based in this fact this review article aims to focus on the possible role of Moringa oleifera as an alternative source of the environmentally friendly product in organic vegetable production. Plant chemicals found in the leaves might help the body process sugar better, and it may affect how the body releases insulin. the activity of the latter compound against a wide range of bacteria and (1992) Commonly used Indian abortifacient plants with special reference SL, AL Udupa, et al. Those who SL Raggett, GL McConnachie, SJT Pollard, V Chipofya, and GA Codd (1997) PL Narasimha Rao (1954) Antibiotic principle from, Das The gum exudates from, Anwar F, and MI Bhanger (2003) Production and hosting by Elsevier B.V. Asian Pacific Journal of Tropical Medicine, https://doi.org/10.1016/j.apjtm.2017.07.002. June, 2000. Is Garcinia Cambogia Safe for Weight Loss? nutritional attributes of seeds from the multiple purpose tree, Olsen In the late 1940’s and early 1950’s a team from the

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